منابع مشابه
Problems with RHAMM A New Link between Surface Adhesion and Oncogenesis?
transformation and metastasis formation when overex-pressed in immortalized murine fibroblasts (Hall et al., 1995). Based on the published cDNA sequence, we raised three polyclonal antibodies recognizing different epi-In a quite spectacular report, a novel mechanism of cell topes in human and murine RHAMM proteins, each of transformation was proposed: a matrix receptor linked which only recogni...
متن کاملInequality Problems of Equilibrium Problems with Application
This paper aims at establishing the existence of results for a nonstandard equilibrium problems $(EP_{N})$. The solutions of this inequality are discussed in a subset $K$ (either bounded or unbounded) of a Banach spaces $X$. Moreover, we enhance the main results by application of some differential inclusion.
متن کاملRHAMM deficiency disrupts folliculogenesis resulting in female hypofertility
The postnatal mammalian ovary contains the primary follicles, each comprising an immature oocyte surrounded by a layer of somatic granulosa cells. Oocytes reach meiotic and developmental competence via folliculogenesis. During this process, the granulosa cells proliferate massively around the oocyte, form an extensive extracellular matrix (ECM) and differentiate into cumulus cells. As the ECM c...
متن کاملRHAMM and CD44 peptides-analytic tools and potential drugs.
CD44 and RHAMM are two extracellar matrix receptors whose principle ligand is the polysaccharide hyaluronan (HA). Both proteins are involved in wound repair and their aberrant regulation contributes to a variety of diseases including arthritis and cancer. Over the past decade, a number of peptide-based therapeutics that block the binding of CD44 or RHAMM-specific ligands have been developed and...
متن کاملRHAMM is a centrosomal protein that interacts with dynein and maintains spindle pole stability.
The receptor for hyaluronan-mediated motility (RHAMM), an acidic coiled coil protein, has previously been characterized as a cell surface receptor for hyaluronan, and a microtubule-associated intracellular hyaluronan binding protein. In this study, we demonstrate that a subset of cellular RHAMM localizes to the centrosome and functions in the maintenance of spindle integrity. We confirm a previ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell
سال: 1998
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(00)81628-1